Master training

Introduction to Pain

Introductory lectures to understand the basics in pain research and treatments

ITP | 3 ECTS

ITP ROF sheet

Timing:

Master 1, Semester 2

Content:

• Establish the fundamentals of Neurobiology of Pain
  Lectures : Concepts, Peripheral mechanisms, Spinal mechanisms, Transmission and pathways, Descending controls, Pharmacology of pain, Higher integration

• Understand stakes and challenges of Pain
  Seminars with Neurobiologists, Pharmacologists/Chemists, Health professionals (Doctors, Nurses, Patients), Psychologists, Sociologist/Philosophers

Targeted skills:

• Acquire the specific vocabulary in the domain of pain

• Understand and manipulate the basic concepts in nociception and pain

• Integrate the different aspects of pain (sensory, affective, cognitive) and their levels of analysis in humans and animals

Person in charge:

Pierrick Poisbeau: poisbeau[at]unistra.fr

Technical Internship

A 6-week laboratory internship

INT | 3 ECTS

Master 1 Internship information

Timing:

Master 1, Semester 2

Content:

• Immerse into a research team and understand the team's research topic and used techniques.

To contact a EURIDOL research team, browse through the list of laboratories of the Strasbourg Pain Initiative

Advanced Lectures in Pain

Interviews with PIs of the Strasbourg Pain Initiative

ALP | 3 ECTS

ALP ROF Sheet

Timing:

Master 2, Semester 3

Content:

• Discover the diversity and complementarity of pain research of the Strasbourg Pain Initiative through meetings with PIs (research in medicine, neuroscience, chemistry, humans and animals)

• Train students in the written and oral synthesis and presentation of these research areas

Targeted skills:

• Understand the specific research programmes in pain developed in the Strasbourg Pain Initiative

• Be able to grasp the stakes of pain research

• Be able to link together and synthesise the different levels and approaches in pain research

Person in charge:

Michel Barrot: mbarrot[at]unistra.fr

Pain Models and Evaluation

Lectures and practicals on the principal models and tests to study pain and nociception in animals

PME | 3 ECTS

PME ROF Sheet

Timing:

Master 2, Semester 3

Content:

Present the various tests and models that exist in animals to study nociception and pain:

• Design and analysis of animal behavioural studies

• Tests and models of nociception in invertebrates

• Nociceptive testing in rodents

• Inflammatory pain models in rodents

• Lesional, metabolic and iatrogenic neuropathic pain models in rodents

• Models of opioid-induced hyperalgesia

• Tests and models of the cognitive consequences of pain in rodents

• Tests and models of the emotional and anxiety-depressive consequences of pain in rodents

• The professional use of animal tests and models by a CRO (Contract Research Organisation)

Train in the description, analysis, interpretation and design of experiments to test a scientific hypothesis in pain research

Targeted skills:

• Know the tests and models in animals

• Describe, analyse and interpret scientific data in pain

• Be able to design an adequate experimental protocol for testing a scientific hypothesis in pain research

Person in charge:

Michel Barrot: mbarrot[at]unistra.fr

Pain at the Clinic

Lectures and practicals on clinical research and medical care (evaluation, pharmacological and non-pharmacological treatments) by specialists in pain in human beings

PAC | 3 ECTS

PAC ROF Sheet

Timing:

Master 2, Semester 3

Content:

Pain in humans

• Clinical management (assessment, drug and non-drug treatments)

• Clinical research (clinical models)

Targeted skills:

• Be able to manipulate the specific concepts and vocabulary of pain in humans

• Be able to appropriate these tools in the analysis of clinic cases

• Be able to transfer in humans the data from preclinical research

Persons in charge:

André Dufour: andre.dufour[at]unistra.fr
Eric Salvat: eric.salvat[at]unistra.fr

Journal Club EURIDOL

Work on recent and major articles to produce a short commentary / review

JCE | 6 ECTS

JCE ROF Sheet

Timing:

Master 2, Semester 3

Content:

Prepare students for scientific writing by writing reviews of scientific articles of major interest in the field of research on pain.

Targeted skills:

• Be able to extract salient information from a scientific paper

• Acquire a critical vision of scientific papers

• Conceive a graphical abstract, a written abstract, and a review

Persons in charge:

Pierrick Poisbeau: poisbeau[at]unistra.fr
Meggane Melchior: mmelchior[at]unistra.fr

Drugs Design & Discovery

Lectures on the world of the conception and production of pharmaceutical drugs

DDD | 3 ECTS

DDD ROF Sheet

Timing:

Master 2, Semester 3

Content:

• The context of the drug world (research, development, production, clinical studies; academic versus industrial environment)

• Jobs available in public organisations (university, CNRS), start-ups, pharmaceutical industry

• Strategies and methods for discovering biologically active molecules: from natural substances; by biotechnology; by rational design (enzymatic inhibition, target modelling); by screening

• The chemistry of molecular interactions between a small molecule and a target protein

• How to modify the structure of a molecule to make it more active in vitro

• How to modify the structure of a molecule to make it more active in vivo

Targeted skills:

• Acquire the knowledge on the strategies and methods to identify and optimise biologically active molecules in pain

• Be able to participate in the discovery and development of a potential drug to alleviate pain

Persons in charge:

Marcella De Giorgi: degiorgi[at]unistra.fr

Line Bourel: line.bourel[at]unistra.fr

Psychosocial Dimensions of Pain

Lectures and seminars with psychology of pain specialists provide a biopsychosocial perspective to the study of pain as well as intervention models from a clinical and well-being perspective

PSP | 3 ECTS

PSP ROF Sheet

Timing:

Master 2, Semester 3

Content:

An introduction regarding psychology, emotions, culture and experience in the influence on the perception and definition of pain, to achieve an integrated understanding of the experience of pain in human beings.

• General basic concepts associated with perception and behaviour

• Integrate these concepts into the clinical practice

Targeted skills:

• Identify the models that explain the perception and behaviour of pain in human beings through an integrated approach

• Understand clinical pain management concepts from a biopsychosocial perspective

• Understand the psychological factors in the perception of pain (personality, culture, gender...)

• Be able to analyse a case study of adult patients with chronic pain from a clinical integrative perspective

Persons in charge:

Iris Chabrier-Trinkler: chabriertrinkler[at]unistra.fr
Andrea Aldana Acosta: aldanaacosta[at]unistra.fr

Master 2 Internship

A 5 to 6-month research internship

INT | 30 ECTS

Master 2 Internship information

Timing:

Master 2, Semester 4

Objectives:

• Integrate into a research team and conduct the Master's work and thesis

To contact a EURIDOL research team, browse through the list of laboratories of the Strasbourg Pain Initiative