Introduction to Pain
Introductory lectures to understand the basics in pain research and treatments
ITP | 3 ECTS
Timing:
Master 1, Semester 2
Content:
Establish the fundamentals of Neurobiology of Pain
Lectures : Concepts, Peripheral mechanisms, Spinal mechanisms, Transmission and pathways, Descending controls, Pharmacology of pain, Higher integration
Understand stakes and challenges of Pain
Seminars with Neurobiologists, Pharmacologists/Chemists, Health professionals (Doctors, Nurses, Patients), Psychologists, Sociologist/Philosophers
Targeted skills:
Acquire the specific vocabulary in the domain of pain
Understand and manipulate the basic concepts in nociception and pain
Integrate the different aspects of pain (sensory, affective, cognitive) and their levels of analysis in humans and animals
Person in charge:
Pierrick Poisbeau: poisbeau[at]unistra.fr
Technical Internship
A 6-week laboratory internship
INT | 3 ECTS
Master 1 Internship information
Timing:
Master 1, Semester 2
Content:
To contact a EURIDOL research team, browse through the list of laboratories of the Strasbourg Pain Initiative
Advanced Lectures in Pain
Interviews with PIs of the Strasbourg Pain Initiative
ALP | 3 ECTS
ALP ROF Sheet
Timing:
Master 2, Semester 3
Content:
Discover the diversity and complementarity of pain research of the Strasbourg Pain Initiative through meetings with PIs (research in medicine, neuroscience, chemistry, humans and animals)
Train students in the written and oral synthesis and presentation of these research areas
Targeted skills:
- Understand the specific research programmes in pain developed in the Strasbourg Pain Initiative
Person in charge:
Michel Barrot: mbarrot[at]unistra.fr
Pain Models and Evaluation
Lectures and practicals on the principal models and tests to study pain and nociception in animals
PME | 3 ECTS
PME ROF Sheet
Timing:
Master 2, Semester 3
Content:
Present the various tests and models that exist in animals to study nociception and pain:
Design and analysis of animal behavioural studies
Tests and models of nociception in invertebrates
Nociceptive testing in rodents
Inflammatory pain models in rodents
Lesional, metabolic and iatrogenic neuropathic pain models in rodents
Models of opioid-induced hyperalgesia
Tests and models of the cognitive consequences of pain in rodents
Tests and models of the emotional and anxiety-depressive consequences of pain in rodents
The professional use of animal tests and models by a CRO (Contract Research Organisation)
Train in the description, analysis, interpretation and design of experiments to test a scientific hypothesis in pain research
Targeted skills:
Know the tests and models in animals
Describe, analyse and interpret scientific data in pain
Be able to design an adequate experimental protocol for testing a scientific hypothesis in pain research
Person in charge:
Michel Barrot: mbarrot[at]unistra.fr
Pain at the Clinic
Lectures and practicals on clinical research and medical care (evaluation, pharmacological and non-pharmacological treatments) by specialists in pain in human beings
PAC | 3 ECTS
PAC ROF Sheet
Timing:
Master 2, Semester 3
Content:
Pain in humans
Targeted skills:
Be able to manipulate the specific concepts and vocabulary of pain in humans
Be able to appropriate these tools in the analysis of clinic cases
Be able to transfer in humans the data from preclinical research
Persons in charge:
André Dufour: andre.dufour[at]unistra.fr
Eric Salvat: eric.salvat[at]unistra.fr
Journal Club EURIDOL
Work on recent and major articles to produce a short commentary / review
JCE | 6 ECTS
JCE ROF Sheet
Timing:
Master 2, Semester 3
Content:
Prepare students for scientific writing by writing reviews of scientific articles of major interest in the field of research on pain.
Targeted skills:
Be able to extract salient information from a scientific paper
Acquire a critical vision of scientific papers
Conceive a graphical abstract, a written abstract, and a review
Persons in charge:
Pierrick Poisbeau: poisbeau[at]unistra.fr
Meggane Melchior: mmelchior[at]unistra.fr
Drugs Design & Discovery
Lectures on the world of the conception and production of pharmaceutical drugs
DDD | 3 ECTS
DDD ROF Sheet
Timing:
Master 2, Semester 3
Content:
The context of the drug world (research, development, production, clinical studies; academic versus industrial environment)
Jobs available in public organisations (university, CNRS), start-ups, pharmaceutical industry
Strategies and methods for discovering biologically active molecules: from natural substances; by biotechnology; by rational design (enzymatic inhibition, target modelling); by screening
The chemistry of molecular interactions between a small molecule and a target protein
How to modify the structure of a molecule to make it more active in vitro
How to modify the structure of a molecule to make it more active in vivo
Targeted skills:
Acquire the knowledge on the strategies and methods to identify and optimise biologically active molecules in pain
Be able to participate in the discovery and development of a potential drug to alleviate pain
Persons in charge:
Marcella De Giorgi: degiorgi[at]unistra.fr
Line Bourel: line.bourel[at]unistra.fr
Psychosocial Dimensions of Pain
Lectures and seminars with psychology of pain specialists provide a biopsychosocial perspective to the study of pain as well as intervention models from a clinical and well-being perspective
PSP | 3 ECTS
PSP ROF Sheet
Timing:
Master 2, Semester 3
Content:
An introduction regarding psychology, emotions, culture and experience in the influence on the perception and definition of pain, to achieve an integrated understanding of the experience of pain in human beings.
Targeted skills:
Identify the models that explain the perception and behaviour of pain in human beings through an integrated approach
Understand clinical pain management concepts from a biopsychosocial perspective
Understand the psychological factors in the perception of pain (personality, culture, gender...)
Be able to analyse a case study of adult patients with chronic pain from a clinical integrative perspective
Persons in charge:
Iris Chabrier-Trinkler: chabriertrinkler[at]unistra.fr
Andrea Aldana Acosta: aldanaacosta[at]unistra.fr
Master 2 Internship
A 5 to 6-month research internship
INT | 30 ECTS
Master 2 Internship information
Timing:
Master 2, Semester 4
Objectives:
To contact a EURIDOL research team, browse through the list of laboratories of the Strasbourg Pain Initiative