Inserm UMR-S (STEP)

Strasbourg Translational NEuroscience and Psychiatry (STEP) | UMR-S  Director: Luc Dupuis

Team "Psychiatry"

Anne Giersch

 email: giersch[at]unistra.fr 

The team aims to understand the pathophysiology of mental diseases, in order to develop new therapies. The team addresses these questions by focusing on a few cognitive disorders, i.e. autobiographical memory, attention and perception disorders, as well as emotional regulation, while aiming to relate them with clinical symptoms, and especially the disorders of the sense of self. Those questions are applied to schizophrenia, depression, post-traumatic disorders, ADHD and borderline personality.  

Research areas: Autobiographical memory ; Attention & perception disorders ; Emotional regulation. 
Techniques: Experimental psychology ; Electroencephalography ; Motion capture ; Eyetracking ; Whole-body motion platform ; Virtual reality. 

Website of Team Psychiatry

 

Team "Addiction"

Laurence Lalanne & Emmanuel Darcq

 email: llalanne[at]unistra.fr & edarcq[at]unistra.fr 

The Addictions team, is based at the CRBS (Centre de Recherche Biomédicale de Strasbourg) in the INSERM STEP Unit, and studies the mechanisms of addictive disorders to opioids, alcohol and cannabis in relation to psychiatric comorbidities. The team is translational, with clinical research led by Laurence Lalanne and pre-clinical research led by Emmanuel Darcq. The clinical research team, focuses on the problem of addictive disorders in relation to psycho-social and epigenetic factors. The pre-clinical team goals are to elucidate the neurobiological mechanisms, and more specifically the brain circuits involved in relapse and abstinence. Pre clinical team is also studying the role of G protein-coupled receptors (GPCRs) in addictive disorders. 

Research areas: Addiction ; Depression ; Opioids ; Cocaine ; cannabis.
Techniques: Clinical techniques and Preclinical ; Behavioural tests ; Optogenetic ; Fiber photometry ; Spatial transcriptomic.

Website of Team "Addiction"