This page provides a sample of the publications of EURIDOL students and researchers of the Strasbourg Pain Initiative. Recent publications are presented first.
"This study used high-speed cooling of the skin and exact control of stimulus duration to measure the cold detection threshold in healthy participants. The objective was to compare the method of limits, in which the temperature is slowly and gradually increased/decreased until the subject perceives…
"In rodents, morphine analgesia is influenced by sex. However, conflicting results exist regarding the interaction between sex and morphine analgesic tolerance. Morphine is metabolized in the liver and brain into morphine-3-glucuronide (M3G). Sex differences in morphine metabolism and differential…
"Rising rates of obesity in most industrialized countries are a major cause of serious medical conditions, including diabetes, heart disease, and mental health disorders. Binge eating, characterized by excessive consumption of highly palatable food within a short period of time, contributes…
"Chronic pain and anxiodepressive disorders are well-known for being intimately related and for influencing each other, but the mechanisms underlying this clinically significant comorbidity remain largely unknown. In this issue, Bravo et al. (2020) address this challenging topic by focusing on brain…
"Chronic pain produces psychologic distress, which often leads to mood disorders such as depression. Co-existing chronic pain and depression pose a serious socio-economic burden and result in disability affecting millions of individuals, which urges the development of treatment strategies targeting…
"Parkinson's disease is a neurodegenerative disorder partly caused by the loss of the dopamine neurons of the nigrostriatal pathway. It is accompanied by motor as well as non-motor symptoms, including pain and depression. The tail of the ventral tegmental area (tVTA) or rostromedial tegmental…
"Reduced pain tolerance may be one of the possible explanations for high prevalence of chronic pain among older people. We hypothesized that age-related alterations in pain tolerance are associated with functioning deterioration of the frontal cortex during normal aging. Twenty-one young and 41…
"The bioheat transfer equation predicts temperature distribution in living tissues such as the skin. This study aimed at psychophysically validating this model in humans. Methods Three experiments were performed. In the first, participants were asked to judge the thermal intensity of stimuli with…
