Publications - EURIDOL - Graduate school of pain - Faculté des sciences de la vie

1 January 2021

Long-lasting analgesic and neuroprotective action of the non-benzodiazepine anxiolytic etifoxine in a mouse model of neuropathic pain

"Neuropathic pain is frequently associated with anxiety and major depressive disorders, which considerably impact the overall patient experience. Favoring GABAergic inhibition through the pain matrix has emerged as a promising strategy to restore proper processing of nociceptive and affective…

2 December 2020

GPRASP/ARMCX Protein Family: Potential Involvement in Health and Diseases Revealed by their Novel Interacting Partners

"GPRASP (GPCR-associated sorting protein)/ARMCX (ARMadillo repeat-Containing proteins on the X chromosome) family is composed of 10 proteins, whose genes are located on a small locus of the X chromosome except one. They possess at least two armadillo-like repeats on their carboxylterminal homologous…

1 December 2020

Accurate Determination of the Cold Detection Threshold with High-Speed Cooling of the Skin

"This study used high-speed cooling of the skin and exact control of stimulus duration to measure the cold detection threshold in healthy participants. The objective was to compare the method of limits, in which the temperature is slowly and gradually increased/decreased until the subject perceives…

1 December 2020

Central metabolism as a potential origin of sex differences in morphine analgesia but not in the induction of analgesic tolerance in mice

"In rodents, morphine analgesia is influenced by sex. However, conflicting results exist regarding the interaction between sex and morphine analgesic tolerance. Morphine is metabolized in the liver and brain into morphine-3-glucuronide (M3G). Sex differences in morphine metabolism and differential…

1 October 2020

Artificial Sweeteners in Animal Models of Binge Eating

"Rising rates of obesity in most industrialized countries are a major cause of serious medical conditions, including diabetes, heart disease, and mental health disorders. Binge eating, characterized by excessive consumption of highly palatable food within a short period of time, contributes…

1 August 2020

Comorbidity of chronic pain and anxiodepressive disorders: Deciphering underlying brain circuits

"Chronic pain and anxiodepressive disorders are well-known for being intimately related and for influencing each other, but the mechanisms underlying this clinically significant comorbidity remain largely unknown. In this issue, Bravo et al. (2020) address this challenging topic by focusing on brain…

1 June 2020

Ketamine induces rapid and sustained antidepressant-like effects in chronic pain induced depression: Role of MAPK signaling pathway

"Chronic pain produces psychologic distress, which often leads to mood disorders such as depression. Co-existing chronic pain and depression pose a serious socio-economic burden and result in disability affecting millions of individuals, which urges the development of treatment strategies targeting…

1 June 2020

Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease

"Parkinson's disease is a neurodegenerative disorder partly caused by the loss of the dopamine neurons of the nigrostriatal pathway. It is accompanied by motor as well as non-motor symptoms, including pain and depression. The tail of the ventral tegmental area (tVTA) or rostromedial tegmental…

1 May 2020

Involvement of Frontal Functions in Pain Tolerance in Aging: Evidence From Neuropsychological Assessments and Gamma-Band Oscillations

"Reduced pain tolerance may be one of the possible explanations for high prevalence of chronic pain among older people. We hypothesized that age-related alterations in pain tolerance are associated with functioning deterioration of the frontal cortex during normal aging. Twenty-one young and 41…

1 May 2020

Thermal sensitivity in humans at the depth of thermal receptor endings beneath the skin: validation of a heat transfer model of the skin using high-temporal resolution stimuli

"The bioheat transfer equation predicts temperature distribution in living tissues such as the skin. This study aimed at psychophysically validating this model in humans. Methods Three experiments were performed. In the first, participants were asked to judge the thermal intensity of stimuli with…

Publications - Page 5 of 5

Long-lasting analgesic and neuroprotective action of the non-benzodiazepine anxiolytic etifoxine in a mouse model of neuropathic pain

GPRASP/ARMCX Protein Family: Potential Involvement in Health and Diseases Revealed by their Novel Interacting Partners

Accurate Determination of the Cold Detection Threshold with High-Speed Cooling of the Skin

Central metabolism as a potential origin of sex differences in morphine analgesia but not in the induction of analgesic tolerance in mice

Artificial Sweeteners in Animal Models of Binge Eating

Comorbidity of chronic pain and anxiodepressive disorders: Deciphering underlying brain circuits

Ketamine induces rapid and sustained antidepressant-like effects in chronic pain induced depression: Role of MAPK signaling pathway

Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease

Involvement of Frontal Functions in Pain Tolerance in Aging: Evidence From Neuropsychological Assessments and Gamma-Band Oscillations

Thermal sensitivity in humans at the depth of thermal receptor endings beneath the skin: validation of a heat transfer model of the skin using high-temporal resolution stimuli

19th annual meeting of the INSERM French pain network in Nice

Bordeaux Summer School 2024 - Neural circuits of pain: from physiology to pathology

Parution de l'ouvrage collectif "Penser le soin pour une médecine humaine et sociale", sous la direction de Philippe Cornet - Préface de Gérard Ostermann.

Science and video games : Euridol PhD-Student Guillaume Reho talks about his participation in the first Scientific Game Jam in Strasbourg

Optical control of PIEZO1 channels

PhD-Student Volodya Hovhannisyan tells us how he organised a symposium on "Sex differences in pain experience and management", which turned out to be larger than expected!

An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats

PhD-Students Robin Kuster and Lucien Ruelle Le Glaunec write about the Pain Summer School in Heidelberg, Oct. 2022

Effect of a web-based app music intervention in the management of chronic pain: a randomised controlled trial by type of pain

PhD-Student Gaëlle Awad attended the "International Drug Association Research Programme" in Nice